Yingjie Zhang Selected Research

2- (2- (3,3- dimethylbutanamido)- 3- methylpentanoyl)- 7- (2- (hydroxyamino)- 2- oxoethoxy)- N- (4- methoxyphenyl)- 1,2,3,4- tetrahydroisoquinoline- 3- carboxamide

8/2014

Superior activity of a new histone deacetylase inhibitor (ZYJ-34c) in inhibiting growth of human leukemia cells by inducing p21WAF1 expression and cell cycle arrest.

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Yingjie Zhang Research Topics

Disease

84	Neoplasms (Cancer) 05/2022 - 07/2004
13	Breast Neoplasms (Breast Cancer) 01/2022 - 04/2011
10	Neoplasm Metastasis (Metastasis) 06/2021 - 08/2011
9	Carcinoma (Carcinomatosis) 01/2020 - 11/2014
8	Colonic Neoplasms (Colon Cancer) 01/2020 - 02/2015
7	Colorectal Neoplasms (Colorectal Cancer) 12/2021 - 07/2017
7	Carcinogenesis 01/2020 - 08/2014
6	Esophageal Neoplasms (Esophageal Cancer) 01/2021 - 01/2017
6	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 11/2011
5	Infections 01/2022 - 10/2014
5	Body Weight (Weight, Body) 02/2019 - 11/2014
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2022 - 09/2013
4	Inflammation (Inflammations) 02/2019 - 10/2008
4	Leukemia 01/2018 - 08/2014
4	Stomach Neoplasms (Stomach Cancer) 01/2016 - 01/2013
3	Autosomal Dominant Polycystic Kidney (ADPKD) 06/2022 - 01/2019
3	Lung Neoplasms (Lung Cancer) 05/2022 - 01/2016
3	Fibrosis (Cirrhosis) 01/2022 - 01/2016
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022 - 08/2014
3	Myopia 01/2022 - 04/2016
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 07/2018
3	Radiation Pneumonitis 01/2021 - 01/2020
3	Thyroid Neoplasms (Thyroid Cancer) 04/2020 - 06/2015
3	Esophageal Squamous Cell Carcinoma 01/2020 - 01/2020
3	Cardiomegaly (Heart Hypertrophy) 02/2019 - 05/2015
3	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2019 - 01/2017
3	Human Influenza (Influenza) 01/2016 - 01/2013
2	Hemorrhage 02/2022 - 01/2020
2	Reperfusion Injury 01/2022 - 01/2015
2	Wounds and Injuries (Trauma) 11/2021 - 01/2015
2	Hepatocellular Carcinoma (Hepatoma) 06/2021 - 10/2015
2	Seroma 05/2021 - 03/2015
2	Heart Failure 01/2021 - 01/2021
2	Cysts 01/2019 - 01/2017
2	Hematologic Neoplasms (Hematological Malignancy) 01/2019 - 01/2019
2	Liver Neoplasms (Liver Cancer) 01/2018 - 11/2016

Drug/Important Bio-Agent (IBA)

19	Proteins (Proteins, Gene)FDA Link 04/2022 - 08/2008
18	Histone Deacetylase InhibitorsIBA 01/2022 - 01/2008
12	Biological ProductsIBA 11/2021 - 10/2008
11	Histone Deacetylases (Histone Deacetylase)IBA 10/2020 - 01/2008
8	Pharmaceutical PreparationsIBA 01/2020 - 12/2010
8	EnzymesIBA 01/2017 - 01/2008
6	Messenger RNA (mRNA)IBA 01/2022 - 05/2015
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2016
6	Antineoplastic Agents (Antineoplastics)IBA 06/2021 - 08/2014
6	Fluorouracil (Carac)FDA LinkGeneric 01/2019 - 02/2015
5	CD13 Antigens (Alanine Aminopeptidase)IBA 06/2021 - 02/2015
5	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 12/2016
5	Vorinostat FDA Link 01/2020 - 04/2011
5	Phosphotransferases (Kinase)IBA 06/2019 - 12/2013
5	ubenimexIBA 01/2018 - 02/2015
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2022 - 09/2006
4	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 01/2017
4	Lysine (L-Lysine)FDA Link 04/2020 - 11/2014
4	Therapeutic UsesIBA 01/2020 - 02/2015
4	HexokinaseIBA 05/2016 - 09/2014
4	fibroblast growth factor 21IBA 01/2016 - 01/2015
3	Docetaxel (Taxotere)FDA Link 04/2022 - 11/2014
3	HydrogelsIBA 03/2022 - 09/2015
3	CytokinesIBA 03/2022 - 01/2015
3	CollagenIBA 01/2022 - 01/2016
3	MicroRNAs (MicroRNA)IBA 01/2021 - 02/2011
3	MatrinesIBA 09/2019 - 01/2017
3	Deoxyglucose (2 Deoxy D glucose)IBA 01/2019 - 05/2016
3	Adenosine Triphosphate (ATP)IBA 01/2019 - 05/2015
3	Angiogenesis InhibitorsIBA 10/2016 - 11/2013
3	Carbon Nanotubes (Carbon Nanotube)IBA 01/2015 - 11/2014
2	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2022 - 11/2014
2	AntibodiesIBA 02/2022 - 06/2015
2	pyrimidineIBA 01/2022 - 11/2021
2	Amino Acids FDA Link 01/2021 - 12/2010
2	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2021 - 01/2017
2	Thyroglobulin FDA Link 04/2020 - 06/2015
2	Histones (Histone)IBA 04/2020 - 01/2017
2	anlotinibIBA 01/2020 - 01/2020
2	Atrial Natriuretic Factor (ANF)IBA 02/2019 - 05/2015
2	Simvastatin (Zocor)FDA LinkGeneric 02/2019 - 12/2016
2	dactolisibIBA 01/2019 - 06/2015
2	Metformin (Glucophage)FDA LinkGeneric 01/2019 - 01/2019
2	palbociclibIBA 01/2019 - 01/2018
2	Hormones (Hormone)IBA 01/2019 - 12/2017
2	DNA (Deoxyribonucleic Acid)IBA 11/2018 - 08/2016
2	ZincIBA 04/2018 - 01/2017
2	pazopanib FDA Link 01/2018 - 01/2017
2	ProdrugsIBA 01/2018 - 10/2016
2	Capecitabine (Xeloda)FDA Link 01/2018 - 10/2016
2	Interleukin-10 (Interleukin 10)IBA 01/2018 - 01/2015
2	cupric sulfide (CuS)IBA 06/2017 - 01/2017
2	Folic Acid (Vitamin M)FDA LinkGeneric 06/2017 - 11/2014

Therapy/Procedure

31	Therapeutics 03/2022 - 01/2008
15	Radiotherapy 04/2022 - 06/2013
6	Drug Therapy (Chemotherapy) 12/2021 - 01/2015
5	Lasers (Laser) 04/2016 - 11/2014
4	Segmental Mastectomy (Lumpectomy) 05/2021 - 01/2012
3	Photothermal Therapy 06/2017 - 01/2015
3	Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated) 01/2016 - 01/2013
2	Transplantation 01/2022 - 01/2016
2	Chemoradiotherapy 01/2020 - 01/2020
2	Image-Guided Radiotherapy 01/2019 - 06/2013
2	Oral Administration 11/2016 - 10/2016